Pharmacy Curriculum Outcomes Assessment (PCOA) Practice Exam

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Hypercalcemia associated with cancer is most often the result of:

  1. Decreased calcium intake

  2. Increased bone reabsorption due to hyperparathyroidism

  3. Renal failure

  4. Vitamin D deficiency

The correct answer is: Increased bone reabsorption due to hyperparathyroidism

Hypercalcemia associated with cancer is most often the result of increased bone reabsorption due to hyperparathyroidism. This is because cancer cells can produce hormones that activate the parathyroid gland, which then leads to increased bone breakdown and release of calcium into the bloodstream. Options A, C, and D are incorrect because they do not involve the parathyroid gland and its role in regulating calcium levels. Decreased calcium intake would result in hypocalcemia rather than hypercalcemia, renal failure would not directly affect the parathyroid gland, and vitamin D deficiency would not cause the parathyroid gland to produce excessive amounts of hormones.

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